• 尊龙凯时·(中国区)人生就是搏!

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    JND003是一种新型选择性ERRα激动剂，可缓解非酒精性脂肪肝和胰岛素抵抗，PK和组织分布测定通过尊龙凯时 - 人生就是搏!进行

    2023-06-28
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    3-JND003-1.jpg

    JND003 is a potent and selective ERRα agonist alleviating nonalcoholic fatty liver disease and insulin resistance. JND003 is orally bioavailable and exhibits high grade of distribution in liver and abdominal adipose tissues. Pharmacokinetics (PK) and Tissue Distribution Assays of JND003 were performed at Medicilon.

    Reference

    Liufeng Mao, et al. Discovery of JND003 as a New Selective Estrogen-Related Receptor α Agonist Alleviating Nonalcoholic Fatty Liver Disease and Insulin Resistance. ACS Bio Med Chem Au. 2022 Jun 15;2(3):282-296. doi: 10.1021/acsbiomedchemau.1c00050.

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